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Cell fate
DC development, lineage specification & epigenetic control
We map enhancers, chromatin accessibility and transcription factor networks to understand how DC subsets emerge from progenitors and acquire specialized functions.
Institute of Experimental Immunology · UZH
Deciphering dendritic cell development, identity and function.
We investigate how dendritic cell subsets develop, acquire specialized functions, and shape immune responses in health and disease.
Research
From progenitors to specialized immune functions.
Three main topics, united by one question: how do transcriptional and epigenetic programs determine what a dendritic cell becomes and what it does?
Mucosal immunity
RORγt⁺ dendritic cells & tolerance
We study RORγt⁺ DCs in food tolerance, peripheral Treg induction, intestinal homeostasis and the regulation of type 2 immunity.
Immune diversity
pDCs and pDC-like derived cDC2
We investigate plasmacytoid DCs, pDC-like cells, cDC2 heterogeneity, and their roles in antiviral immunity, autoimmunity and cancer.
People
A growing team working on DC immunology.
- Research position
- Group Leader
- Research interests
- Dendritic cell development, immune tolerance, transcriptional and epigenetic control
- Nationality
- Portuguese
- Position
- Administrative Assistant
- Email Carmen
- Telephone
- +41 44 635 37 02
PhD Student
Open position
PhD Student
Open position
Master Student
Open position
Master Student
Open position
The Rodrigues Lab is a team where everyone contributes equally to science. Our research focuses on dendritic cell development, immune tolerance, and the transcriptional and epigenetic mechanisms that control immune cell specialization.
Publications
Selected work.
Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells.
Nature ImmunologyPubMed Central 
DOI
News
Latest from the lab.
Rodrigues Lab launching at the University of Zurich.
We are excited to officially launch the Rodrigues Lab at the University of Zurich’s Institute of Experimental Immunology, where we investigate dendritic cell development, identity and immune function.
Read more ↗We are recruiting motivated team members.
PhD students and Master/Bachelor students with a passion for immunology and genomics are encouraged to get in touch.
Read more ↗Contact
Get in touch.
Interested in a position, a collaboration, or simply a chat about dendritic cells? We’d love to hear from you.
Contact the lab
For positions, collaborations and scientific enquiries.
Institute of Experimental ImmunologyUniversity of Zurich
Winterthurerstrasse 1908057 Zürich, Switzerland